Marwan Sabbagh Selected Research

ALZ-801

12/2020

Aducanumab, gantenerumab, BAN2401, and ALZ-801-the first wave of amyloid-targeting drugs for Alzheimer's disease with potential for near term approval.

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Marwan Sabbagh Research Topics

Disease

45	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2003
12	Dementia (Dementias) 06/2021 - 07/2011
10	Cognitive Dysfunction 06/2021 - 12/2005
4	Inflammation (Inflammations) 01/2020 - 01/2009
4	Parkinson Disease (Parkinson's Disease) 10/2017 - 11/2009
3	Down Syndrome (Down's Syndrome) 01/2022 - 02/2015
3	Amyloid Plaque 12/2020 - 01/2007
3	Disease Progression 12/2020 - 01/2014
2	Edema (Dropsy) 12/2020 - 01/2014
2	Heart Diseases (Heart Disease) 12/2004 - 01/2003
1	Brain Diseases (Brain Disorder) 01/2021
1	Cerebral Cortical Thinning 01/2020
1	Atrophy 01/2020
1	Intellectual Disability (Idiocy) 05/2017
1	Deglutition Disorders (Dysphagia) 08/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2014
1	Vascular System Injuries 01/2012
1	Insulin Resistance 01/2012
1	Diabetes Mellitus 01/2012
1	Amyloid angiopathy 04/2010
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2009
1	Stroke (Strokes) 01/2009
1	Intracranial Arteriosclerosis (Cerebral Atherosclerosis) 01/2007
1	Tauopathies 07/2003
1	Hypercholesterolemia 01/2003

Drug/Important Bio-Agent (IBA)

13	Amyloid (Amyloid Fibrils)IBA 01/2022 - 04/2010
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2009
8	Donepezil (Aricept)FDA LinkGeneric 01/2021 - 02/2011
6	Amyloid beta-PeptidesIBA 01/2022 - 03/2004
5	ApolipoproteinsIBA 01/2020 - 01/2007
5	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2020 - 02/2011
5	CholesterolIBA 10/2018 - 01/2003
4	Apolipoprotein E4IBA 12/2020 - 12/2012
4	Memantine (Namenda)FDA Link 01/2020 - 02/2011
4	Pharmaceutical PreparationsIBA 01/2020 - 12/2012
3	Apolipoproteins E (ApoE)IBA 01/2020 - 04/2010
3	Monoclonal AntibodiesIBA 06/2014 - 03/2012
3	Receptor for Advanced Glycation End ProductsIBA 01/2014 - 01/2009
3	Proteins (Proteins, Gene)FDA Link 06/2013 - 11/2009
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2018 - 01/2013
2	Investigational DrugsIBA 01/2015 - 06/2014
2	bapineuzumabIBA 01/2014 - 03/2012
2	LigandsIBA 01/2012 - 01/2009
2	Cholinergic Agents (Cholinergics)IBA 01/2012 - 02/2011
2	LipidsIBA 12/2004 - 01/2003
2	Triglycerides (Triacylglycerol)IBA 12/2004 - 01/2003
1	Indicators and Reagents (Reagents)IBA 01/2022
1	Choline (Choline Chloride)IBA 06/2021
1	UridineIBA 06/2021
1	Docosahexaenoic AcidsIBA 06/2021
1	Neuroprotective AgentsIBA 06/2021
1	Biological ProductsIBA 01/2021
1	serotonin 6 receptorIBA 01/2021
1	3- benzenesulfonyl- 8- piperazin- 1- ylquinolineIBA 01/2021
1	aducanumabIBA 12/2020
1	gantenerumabIBA 12/2020
1	lecanemabIBA 12/2020
1	ALZ-801IBA 12/2020
1	tramiprosateIBA 01/2020
1	salicylhydroxamic acid (SHAM)IBA 01/2020
1	Complement System Proteins (Complement)IBA 11/2018
1	Complement Receptors (Complement Receptor)IBA 11/2018
1	Peptides (Polypeptides)IBA 11/2018
1	flutemetamolIBA 01/2018
1	4- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA 02/2015
1	tau Proteins (tau Protein)IBA 01/2015
1	azeliragonIBA 01/2014
1	MicroRNAs (MicroRNA)IBA 01/2014
1	RNA (Ribonucleic Acid)IBA 01/2014
1	florbetapirIBA 01/2013
1	RadiopharmaceuticalsIBA 01/2013
1	Rivastigmine (Exelon)FDA LinkGeneric 12/2012
1	N-(2-naphthalene)sulfonyl-DL-tryptophan (A 91)IBA 02/2012
1	Glucose (Dextrose)FDA LinkGeneric 01/2012
1	AcetylcholinesteraseIBA 01/2012
1	Celecoxib (Celebrex)FDA Link 07/2011
1	Naproxen (Naprosyn)FDA LinkGeneric 07/2011
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/2011
1	Excitatory Amino Acid AntagonistsIBA 02/2011
1	ORALIT (ORS)IBA 01/2007
1	Ceruloplasmin (Ferroxidase)IBA 12/2005
1	oxidized low density lipoproteinIBA 12/2004
1	Lipoproteins (Lipoprotein)IBA 12/2004
1	HDL LipoproteinsIBA 12/2004
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 03/2004
1	SilverIBA 07/2003
1	HDL CholesterolIBA 01/2003

Therapy/Procedure

7	Therapeutics 01/2021 - 12/2004
2	Activities of Daily Living (ADL) 01/2021 - 06/2013
1	Cognitive Training 01/2020
1	Transcranial Magnetic Stimulation 01/2020
1	Deep Brain Stimulation 01/2016